The Razor's Edge:
Balancing Chemical Protection and Thermal Strain in CBRN Operations
By Adam Potter, Madeline Poley-Bogan, Karleigh Bradbury, Karl Friedl, and William Tharion
Article published on: January 1, 2026 in the Army Chemical Review 2026 issue of the Army
Chemical Review
Read Time: < 11 mins
Figure 1: Trade-offs in CBRN Protection and heat dissipation. There is an inverse relationship
between protection from CBRN threats and the human body’s ability to dissipate heat.
The contents of this article do not represent the official views of, nor are they endorsed by, the U.S. Army,
the Department of War (DoW), or the U.S. Government.
This article was edited with the assistance of AI tools, and subsequently reviewed and edited by relevant
Department of War (DoW) personnel to ensure accuracy, clarity, and compliance with DoW policies and guidance.
Introduction
Balancing robust Chemical, Biological, Radiological, Nuclear (CBRN) protection with minimal thermal strain is
critical for warfighter readiness and operational effectiveness. The inherent impermeability of chemical protective
clothing (CPC), while blocking hazardous agents, imposes a significant thermal and physiological burden, as seen in
Figure 1. By restricting natural cooling mechanisms, CPC leads to heat stress, performance degradation, and
potentially life-threatening hyperthermia (heat stroke). The ultimate goal is to safeguard operators from CBRN
threats while mitigating the severe risks of heat illness, injury, and fatality.
The U.S. Army Research Institute of Environmental Medicine (USARIEM) addresses this challenge through a vertically
integrated scientific approach. As the premier human performance laboratory for the Department of War (DoW), USARIEM
provides guidance on material solutions and develops standard operating procedures (SOPs) for CBRN personnel. The
work at USARIEM spans the entire developmental lifecycle: from foundational research on heat transfer and basic CPC
testing to post-acquisition assessments of fielded solutions. All this is to rigorously evaluate effectiveness,
usability, and operator acceptance based on controlled studies and real-world utilization.
The Challenge: Chemical Protection vs. Thermal Strain
CPC is designed with impermeable or selectively permeable materials that block hazardous agents. This barrier,
however, also impedes the evaporation of sweat—the body's primary means of dissipating heat. The trapped moisture
increases humidity within the suit, further hindering evaporative cooling and leading to a rapid rise in skin and
core body temperatures. The physiological consequences of this thermal burden are significant:
- Impaired cognitive function: Heat stress can degrade decision making, reaction time, and
overall cognitive performance.
- Decreased physical performance: Muscle fatigue, dehydration, and cardiovascular strain limit
physical endurance and strength.
- Increased risk of heat illness: Prolonged exposure to high heat and humidity, especially
during exercise or while wearing CPC, significantly increases the risk of heat exhaustion, heat stroke, and death.
Optimizing CPC design and operational strategies is therefore a critical need for the military to minimize thermal
strain without compromising protective capabilities.
USARIEM's Role: Assessing and Predicting Thermal Burden
Figure 3: Human Subjects Research in Climate Chamber. Soldiers in a climate-controlled chamber,
instrumented with body-worn sensors, simulating marching activities while in different chemical protective
clothing.(Photo by David Kamm)
USARIEM employs a multifaceted approach to understand and mitigate the physiological burden of CPC, combining
controlled laboratory studies, predictive modeling, and real-world field deployments.
Biophysical Clothing Assessments Using Specialized Thermal Manikins
USARIEM uses advanced thermal manikins to build a foundational understanding of how clothing impacts human
physiology, as seen in Figure 2. These manikins mimic human thermoregulation, including sweating rates and skin
temperature regulation. In controlled climate chambers, researchers precisely measure the thermal and evaporative
resistance of different CPC configurations, quantifying the inherent burden a suit will impose.1 This work provides critical data on heat exchange characteristics,
including:
- Thermal resistance: The measure of dry heat exchange or insulation provided by clothing.
- Evaporative resistance: The measure of resistance to moisture vapor transfer through clothing,
indicating how much sweat can evaporate.
- Water vapor permeability: The ease with which water vapor passes through the material.
- Wind effects on biophysics: The influence of wind on biophysical properties, revealing
environmental impacts on protection or burden.
Controlled Human Laboratory Trials
Figure 2: USARIEM’s Specialized Thermal Manikins. USARIEM’s sweating thermal manikins being used
to evaluate the biophysical properties of chemical protective clothing in a controlled climate chamber (left),
undressed manikin with articulated walking system (right). (Photo by Madeline Poley-Bogan)
USARIEM conducts rigorous, direct human studies in state-of-the-art climate chambers.2 Human volunteers perform simulated military tasks or exercise
protocols while wearing various CPC configurations under precisely controlled temperature, humidity, and wind
conditions, as shown in Figures 3 and 4. A comprehensive suite of physiological parameters (core and skin
temperatures, heart rate, metabolic rate, sweat rate, and hydration status) and performance metrics (physical and
cognitive) are continuously monitored. These laboratory studies may be conducted if the system or conditions of use
are substantially different than previously tested and modeled systems. Otherwise, model predictions can provide
immediate assessment as the physiological models should have already been used in the development of a new CPC. The
lab studies provide empirical data used for further validating models. As noted, these models are used by materiel
developers early in the development of new ensembles, and by combat developers for evidence-based guidelines for
safe operations.
Advanced Predictive Modeling
USARIEM has developed mathematical models that predict the physiological responses of warfighters wearing CPC
under various environmental conditions and activity levels. This began with the massive 1985 P2NBC (Physiological
and Psychological Effects of the NBC Environment and Protective Equipment) program, when USARIEM was asked to
develop early predictive thermal models.3 The
models have continued to develop, incorporating more conditions, and evolving from average group predictions to
detailed personalized forecasts including algorithms linked to wearable physiological monitoring. These models
incorporate a wide array of human-centric and environmental factors, including individual characteristics (age,
fitness, acclimatization, metabolic rate), clothing properties (thermal and evaporative resistance, permeability),
environmental conditions (temperature, humidity, wind, solar radiation), and terrain.
One key tool is the Heat Strain Decision Aid (HSDA), an empirically based thermoregulatory model that predicts
core body temperature by integrating inputs related to the individual, clothing values, environmental conditions,
and activity.4 The HSDA relies on the heat balance
equation, accounting for heat production, environmental heat gain, and heat dissipation. It has been instrumental in
quantifying critical details for major guidance documents, such as the U.S. Army Technical Bulletin Medical (TB Med)
507,5 and has since been transitioned to multiple
DoW organizations and international partners.
Real-Time Physiological Status Monitoring and Field Studies
Bridging the gap between laboratory predictions and dynamic, real-world variability, USARIEM leads the development
and deployment of Real-Time Physiological Status Monitoring (RT-PSM) systems. As seen in Figure 5, these wearable
sensors continuously collect individualized physiological data (core and skin temperatures, heart rate, respiration
rate, activity levels) from users in operational or simulated field environments. RT-PSM provides real-time
assessments of a Soldier's status, allowing for timely intervention to prevent heat illness and providing empirical
data to refine protective strategies and future CPC designs. USARIEM has led development and technical oversight for
both commercial and government RT-PSM solutions and pursues its own algorithm development for health status
predictions.
Figure 4: Human Subject Research in Climate Chamber (Marching Simulation). A USARIEM scientist
(Dr. Karleigh Bradbury) monitoring Soldiers in a climate-controlled chamber, instrumented with body-worn sensors,
simulating marching activities while in chemical protective clothing.(Photo by David Kamm)
Real-World Impact and Continuous Improvement: The Civil Support Team Initiative
The National Guard Bureau Weapons of Mass Destruction – Civil Support Teams (CSTs) are specialized units
responsible for responding to CBRN incidents domestically. Given the inherent thermal and respiratory risks
associated with full encapsulation, CSTs are prime candidates for early implementation of RT-PSM technologies and
leveraging USARIEM's modeling capabilities, including the HSDA. The National Guard Bureau, co-led by USARIEM through
an integrated product team (IPT), has led a nationwide effort to integrate RT-PSM into all 57 CST units.6 This comprehensive initiative encompasses the
deployment of multiple technologies—including a wearable physiological device, a communication element, and an
end-user display—and necessitates diverse expertise for successful system integration.
This initiative involves:
- Technology evaluation: Rigorous testing of commercially available RT-PSM systems for
reliability, accuracy, and user-friendliness in CST applications.
- Training and education: Comprehensive programs for CST personnel on RT-PSM use, sensor
placement, data interpretation, and intervention strategies.
- Integration into operational protocols: Development of SOPs for integrating RT-PSM data into
CBRN response decision making.
- Data analytics and reporting: Establishment of platforms to track physiological trends,
identify risk factors, and improve heat mitigation strategies.
This comprehensive rollout also includes rigorous post-acquisition and deployment assessments, critical for
continuous improvement.7 Surveys and structured
focus groups with experienced CST users (6+ months of use) revealed valuable insights. While 97% of respondents
believed a system meeting their expectations would be useful, only 60% found the fielded RT-PSM system acceptable.
Primary drawbacks included communications issues, lengthy setup times, and system unreliability. Though not a
deciding factor for acceptability, the chest harness design was also reviewed negatively.8 This feedback is crucial for refining RT-PSM technologies and
expanding their application to other military and civilian CBRN response units.
Figure 5: Real-Time Physiological Status Monitoring (RT-PSM) in Field Training. 95th Civil
Support Team Soldiers conducting training while instrumented with RT-PSM systems, including a prototype external
buddy display showing individualized health metrics. The arm-mounted display on the right shows a low (green) risk
metric of 2 on a 1-10 scale (10 being significant risk of heat injury). (Photo by William Tharion)
Conclusion
Balancing chemical protection and thermal strain remains a critical challenge in CBRN operations. USARIEM's
comprehensive research efforts, including controlled human trials, advanced clothing assessments with thermal
manikins, sophisticated predictive modeling such as HSDA, and the development and deployment of RT-PSM technologies,
are essential for mitigating the physiological burden imposed by CPC. The ongoing rollout of RT-PSM to National
Guard Bureau CSTs exemplifies the commitment to leveraging innovation to protect our nation's first responders and
enhance their ability to respond to CBRN threats. Continued research and development are crucial for forming the
next generation of CPC and optimizing operational strategies to minimize thermal strain and maximize warfighter
performance in the face of evolving CBRN challenges. The "razor's edge" between robust protection and optimal
performance demands constant vigilance and innovation to ensure warfighters can operate safely and effectively in
the most demanding CBRN environments.
Endnotes
1. Potter AW, Gonzalez JA, Karis AJ, Blanchard LA, Rioux TP,
and Santee WR, Biophysical characteristics of chemical protective ensemble with and without body armor, (Natick,
MA: United States Army Research Institute of Environmental Medicine, Technical Report T15-8, 2015).
2. Potter AW, Hunt AP, Cadarette BS, Fogarty A, Srinivasan S,
Santee WR, Blanchard LA, and Looney DP, “Heat Strain Decision Aid (HSDA) accurately predicts individual-based core
body temperature rise while wearing chemical protective clothing,” Computers in Biology and Medicine, no. 107
(2019): 131-136.
3. Santee WR, Matthew WT, and Tharion WJ, Simulated approach
marches during thermal stress: a P2NBC2 study, (Natick, MA: United States Army Research Institute of Environmental
Medicine, Technical Report T12-92, 1992).
4. Potter AW, Blanchard LA, Friedl KE, Cadarette BS, and Hoyt
RW, “Mathematical prediction of core body temperature from environment, activity, and clothing: The heat strain
decision aid (HSDA),” Journal of Thermal Biology, no. 64 (2017): 78-85.
5. US Army, Heat Stress Control and Heat Casualty Management,
(Washington, DC: Technical Bulletin, Medical, 507, 2022).
6. Tharion WJ, Maeder S, and Jones R, “Fielding military health
status wearables,” Army Acquisition Logistics and Technology (AL&T) Magazine Supplement 2022 Major General
Harold J. “Harry” Greene Awards for Acquisition Writing, Spring 2023, 26-30. https://asc.army.mil/web/wp-content/uploads/2023/04/2021_acq_writing_awards-proof_final.pdf.
7. Tharion WJ, Halford EN, and Potter AW, Post Acquisition
Surveillance Monitoring of the Fielding of Physiological Status Monitoring (PSM) Systems to the Weapons of Mass
Destruction – Civil Support Teams (WMD-CSTs), (Natick, MA: United States Army Research Institute of Environmental
Medicine, Technical Report T25-005, 2025).
8. Ibid.
Authors
Adam W. Potter, Ph.D., is a Research Physiologist at the U.S. Army Research Institute of
Environmental Medicine (USARIEM). Dr. Potter leads mathematical physiology research, developing predictive models
for Army planners, decoding sensor information for real-time decision-making, and uncovering complex data
relationships to identify new health and performance readiness metrics.
Madeline M. Poley-Bogan, M.S., is a Research Fellow at the U.S. Army Research Institute of
Environmental Medicine (USARIEM). She specializes in biophysics, modeling the combined effects of clothing,
weather conditions, and human physiology through specialized human manikin technologies originally developed by
the Army.
Karleigh E. Bradbury, Ph.D., is a Research Physiologist at the U.S. Army Research Institute of
Environmental Medicine (USARIEM) and a DoW SMART Scholar. Her work spearheads Army research in human performance,
environmental physiology, and thermoregulation, specifically addressing the physiological impacts of exercise and
stressors while wearing chemical protective clothing during military operations.
Karl E. Friedl, Ph.D., Colonel (MSC, Army, retired), is a Science and Technology leader and a
member of the Senior Executive Service (ST/SES). As the Chief Physiologist for the U.S. Army, he conceives and
champions physiological research to create new options and solutions for future Soldiers.
William Tharion, MS, MBA, is a Research Psychologist at the U.S. Army Research Institute of
Environmental Medicine (USARIEM). Mr. Tharion is the technical lead for the transition of real-time sensing
capabilities to the National Guard Bureau. His expertise spans cognitive sciences, wearables, and human
performance, with a demonstrated ability to provide actionable solutions for service members.